Chemistry in the News
New chemical technology boosts potency of targeted cancer therapy
Thu, 21 May 2015 14:40:32 EDT
A new chemical technology uses cancer cells' own protein-degrading machinery to destroy, rather than merely inhibit, cancer proteins. Researchers developed the strategy as a way to develop inhibitors of "undruggable" proteins and overcome drug resistance, a common shortcoming of targeted therapies. Resistance arises when tumors that originally responded to a particular therapy manage to circumvent the drug's effects and resume their growth.
Implantable micro-device to monitor oxygen in glioma to improve treatment outcomes
Thu, 21 May 2015 14:38:19 EDT
Monitoring oxygen levels in human tumors growing in a mouse brain using EPR oximetry with implantable resonators provides opportunities to evaluate and optimize various strategies being developed to improve oxygen levels in the glioma.
Modern alchemy: Chemists devise synthesis of valuable exotic compounds
Thu, 21 May 2015 08:22:56 EDT
A broad and strikingly inexpensive method for synthesizing "amines," a class of organic compounds prominent in drugs and other modern products, has been discovered by a group of chemists. The new reaction is particularly useful for synthesizing complex amines that would be highly valuable in pharmaceuticals, but are impractical -- or impossible -- to make with standard methods.
Shining light on the fleeting interactions of single molecules
Thu, 21 May 2015 08:16:49 EDT
Scientists have devised a way of directly detecting and visualizing biomolecules and their changing association states in solution by measuring their size and charge characteristics while confined in a single-molecule trap.
Mesoporous particles for the development of drug delivery system safe to human bodies
Wed, 20 May 2015 15:13:34 EDT
Scientists have succeeded in developing porous particles (mesoporous particles) consisting solely of phospholipids, a biological component, that are suitable for use as a drug delivery system.