How the smallest bacterial pathogens outwit host immune defenses by stealth mechanisms
Fri, 20 Oct 2017 10:16:24 EDT
Despite their relatively small genome, mycoplasmas can cause persistent and difficult-to-treat infections in humans and animals. A study has shown how mycoplasmas escape the immune response. Mycoplasmas 'mask' themselves: They use their small genome in a clever way and compensate for the loss of an enzyme that is important for this process. This could be shown for the first time in vivo, thus representing a breakthrough in the research of bacterial pathogens.
Chromosomes may be knotted
Fri, 20 Oct 2017 10:16:18 EDT
Little is known about the structures of our genetic material, chromosomes, which consist of long strings that -- according to our experience -- should be likely to become knotted. However, up to now it has not been possible to study this experimentally. Researchers have now found that chromosomes may indeed be knotted.
Gut bacteria from wild mice boost health in lab mice
Thu, 19 Oct 2017 14:30:12 EDT
Laboratory mice that are given the gut bacteria of wild mice can survive a deadly flu virus infection and fight colorectal cancer dramatically better than laboratory mice with their own gut bacteria, researchers report.
H7N9 influenza is both lethal and transmissible in animal model for flu
Thu, 19 Oct 2017 14:30:07 EDT
In 2013, an influenza virus began circulating among poultry in China. It caused several waves of human infection and as of late July 2017, nearly 1,600 people had tested positive for avian H7N9. Nearly 40 percent of those infected had died. In 2017, a medical researcher received a sample of H7N9 virus isolated from a patient in China who had died of the flu. He and his research team subsequently began work to characterize and understand it.
Gut bacterium indirectly causes symptoms by altering fruit fly microbiome
Thu, 19 Oct 2017 14:27:24 EDT
CagA, a protein produced by the bacterium Helicobacter pylori, can alter the population of microbes living in the fruit fly gut, leading to disease symptoms, according to new research.