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Study Questions 1. Is cortical rotation necessary for the formation of the Nieuwkoop center?
2. Can you predict the effect of injecting an antisense oligonucleotide against Noggin mRNA into a Xenopus embryo?
3. Speculate on how a morphogen, for example activin, could bring about different kinds of differentiation depending on the concentration to which responding cells are exposed.
4. In amniote embryos, the neural tube and somites form sequentially from anterior to posterior end. What might be responsible for this?
5. Predict the outcome of an experiment in which the expression of the gene radical fringe is reduced by a loss-of-function mutation. What would be the effect on the wing bud?
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